Design and Fabrication of a Hybrid 3D Bioprinter

Abstract

3D bioprinting is a newly developed technology to fabricate artificial tissues and organs through additive manufacturing of living cells into a 3D tissue structure layer by layer. In this project, Dr. Truong and his collaborators are developing a hybrid 3D system of which one head is dedicated for printing complex scaffold structures from various biomaterials, and other heads are for accurately dispensing minuscule volumes of bio-ink and growth factors.

The research objectives are as follows:

Aim 1: Develop a novel multi-head hybrid 3D bioprinter for tissue engineering high resolution and accuracy.

Aim 2: Develop a computer aided bioprinting design to quickly construct a 3D structure with controlled hybrid architecture for ensuring mechanical strength and biological behavior.

Aim 3: Carry out in vitro culture tests to evaluate the biocompatibility and proliferation of several cells, and to find out the preferred scaffold architecture for bioprinting.

Author: Do Tho Truong

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